Laboratory of Molecular Pharmacology/Division for Bone Research, School of Health Sciences, University of Patras, Patras 26504, Greece. Electronic address: angkaspiris@hotmail.com. 1st Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, Medical School, "ATTIKON" University Hospital, Athens, Greece. 2nd Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, Medical School, Konstantopoulio General Hospital, Athens 14233, Greece. 3nd Department of Orthopaedic Surgery, National and Kapodistrian University of Athens, Medical School, KAT General Hospital, Athens 14561, Greece.